Definition of Zosuquidar Trihydrochloride

A difluorocyclopropyl quinoline. Zosuquidar trihydrochloride binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). P-glycoprotein, encoded by the MDR-1 gene, is a member of the ATP-binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product-derived cytotoxic agents. (NCI04)

Zosuquidar Trihydrochloride is from the group

Multidrug Resistance Modulator

Other Names for Zosuquidar Trihydrochloride

Zosuquidar Trihydrochloride
LY335979
zosuquidar trihydrochloride

Source

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Topics #Zosuquidar Trihydrochloride LY335979 zosuquidar trihydrochloride