Definition of Zolmitriptan

A member of the triptan class agents with anti-migraine property. Zolmitriptan selectively binds to and activates serotonin (5-HT) 1B expressed in intracranial arteries and 5_HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. receptor binding results in constriction of cranial vessels, reduction of the vessel pulsation and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Zolmitriptan may also relief migraine headaches by inhibition pro-inflammatory neuropeptide release.

Zolmitriptan is from the group

Serotonin Agonist

Other Names for Zolmitriptan

Zolmitriptan
2-Oxazolidinone, 4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)-,(S)-
311C90
ZOLMITRIPTAN
Zomig

Source

NCI Thesaurus License

Topics #(S)- 311C90 ZOLMITRIPTAN Zomig #4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)- #Zolmitriptan 2-Oxazolidinone