Definition of Zolimomab Aritox

An immunotoxin consisting of a murine anti-CD5 monoclonal antibody conjugated to the ricin A chain. The anti-CD5 monoclonal antibody component binds to CD5, a T-cell associated antigen, thereby targeting the delivery of the cytotoxic ricin a chain to T-cells. The ricin a chain component binds to T-cells and disrupts ribosomal activity and protein synthesis and induces cell cycle arrest. (NCI04)

Zolimomab Aritox is from the group

Ricin Immunoconjugate

Other Names for Zolimomab Aritox

Zolimomab Aritox
Anti-CD5 MoAb
Anti-CD5 T-Lymphocyte Immunotoxin
Anti-T-Cell RTA Immunotoxin
Anti-T-Cell Ricin A Chain Immunotoxin
CD5-Immunoconjugate
H65-RTA
Orthozyme-CD5 Plus
XomaZyme-CD5 Plus

Source

NCI Thesaurus License

Topics #Zolimomab Aritox Anti-CD5 MoAb Anti-CD5 T-Lymphocyte Immunotoxin Anti-T-Cell RTA Immunotoxin Anti-T-Cell Ricin A Chain Immunotoxin CD5-Immunoconjugate H65-RTA Orthozyme-CD5 Plus XomaZyme-CD5 Plus