Definition of ZD-6126

A water-soluble phosphate prodrug of N-acetylcolchinol with potential antineoplastic activity. ZD-6126 binds to and destabilizes the tubulin cytoskeleton of endothelial cells, thereby inhibiting angiogenesis which may result in tumor necrosis. (NCI04)

ZD-6126 is from the group

Endothelial Cell Inhibitor

Other Names for ZD-6126

ZD-6126
ANG453
N-[(5S)-6,7-Dihydro-9,10,11-trimethoxy-3-(phosphonooxy)-5H-dibenzo[a,c]cyclohepten-5-yl]acetamide
N-acetylcochinol-O-phosphate
ZD6126

Source

NCI Thesaurus License

Topics #10 #11-trimethoxy-3-(phosphonooxy)-5H-dibenzo[a #7-Dihydro-9 #c]cyclohepten-5-yl]acetamide N-acetylcochinol-O-phosphate ZD6126 #ZD-6126 ANG453 N-[(5S)-6