Definition of Zanamivir

A sialic acid analog and a neuraminidase inhibitor with antiviral property. Zanamivir selectively inhibits influenza A and B virus neuraminidase, a viral surface glycoprotein, which mediates the cleavages of sialic acid residues on the surfaces of host cells and influenza viral envelopes. The uncleaved sialic acid residues were bound by viral hemagglutinin, thereby resulting in viral aggregation at the host cell surface, thereby preventing the release of influenza virus particles into the respiratory tract.

Zanamivir is from the group

Miscellaneous Antiviral Agent

Other Names for Zanamivir

4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic Acid
5-Acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic Acid
GG 167


NCI Thesaurus License

Topics #3-dehydro-N-acetylneuraminic Acid 5-Acetamido-2 #4 #4-dideoxy-2 #5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic Acid GANA GG 167 Relenza ZANAMIVIR #6-anhydro-3 #Zanamivir 4-Guanidino-2