Definition of Xeroderma Pigmentosum Complementation Group-A Protein

DNA-Repair protein Complementing XP-A Cells (XPA), the nuclear protein encoded by the XPA gene, has a zinc finger domain and is involved in the DNA excision repair pathway. XPA initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. XPA complements the defect in xeroderma pigmentosum (XP) group A (XP-A), an autosomal recessive disease characterized by hypersensitivity of the skin to sunlight followed by high incidence of skin cancer and frequent neurologic abnormalities. Group A patients show the most severe skin symptoms and progressive neurological disorders.

Xeroderma Pigmentosum Complementation Group-A Protein is from the group

DNA Repair Protein

Other Names for Xeroderma Pigmentosum Complementation Group-A Protein

Xeroderma Pigmentosum Complementation Group A Protein
XPA
Xeroderma Pigmentosum Group A Complementing Protein

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Topics #Xeroderma Pigmentosum Complementation Group A Protein XPA Xeroderma Pigmentosum Group A Complementing Protein