Definition of Wolf-Hirschhorn Syndrome Candidate-1 Protein

Encoded by human oncogene WHSC1 Gene, 1365-amino acid 152 kD Wolf-Hirschhorn syndrome Candidate 1 protein contains a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. WHSC1 is preferentially expressed in rapidly growing embryonic tissues, in a pattern corresponding to affected organs in WHS patients. The nature of the protein motifs and expression pattern suggest that WHSC1 is a good candidate responsible for many of the phenotypic features of WHS — a malformation syndrome associated with hemizygous deletion of the chromosome 4 distal short arm. (OMIM, Swiss-Prot, LocusLink, and NCI)

Wolf-Hirschhorn Syndrome Candidate-1 Protein is from the group

Ligase

Other Names for Wolf-Hirschhorn Syndrome Candidate-1 Protein

Wolf-Hirschhorn Syndrome Candidate 1 Protein
MMSET Protein
Multiple Myeloma Set Domain Protein
NSD2 Protein
Nuclear Set Domain-Containing 2 Protein
WHSC1
WHSC1 Protein

Source

NCI Thesaurus License

Topics #Wolf-Hirschhorn Syndrome Candidate 1 Protein MMSET Protein Multiple Myeloma Set Domain Protein NSD2 Protein Nuclear Set Domain-Containing 2 Protein WHSC1 WHSC1 Protein