Definition of WFDC1 Protein

Encoded by human WFDC1 Gene, the 220-amino acid 24 kD (precursor) secretory Prostate Stromal protein ps20 (WAP Family) is a growth inhibitor that contains a WAP four-disulfide core domain characteristic of protease inhibitors. The WAP signature motif contains eight cysteines forming four disulfide bonds at the core of proteins that functions as a protease inhibitor in many family members. Human ps20 shares approximately 86% and 88% identity with the rat and mouse secreted growth inhibitor proteins. Loss of ps20 is associated with prostate, breast, and hepatocellular cancers and Wilms’ tumor. (from SWISS-PROT, OMIM, Proteome, and NCI)

WFDC1 Protein is from the group

Extracellular Protein

Other Names for WFDC1 Protein

WFDC1 Protein
Prostate Stromal Protein ps20
WAP Four-Disulfide Core Domain 1 Protein
WFDC1

Source

NCI Thesaurus License

Topics #WFDC1 Protein Prostate Stromal Protein ps20 WAP Four-Disulfide Core Domain 1 Protein WFDC1