Definition of Valspodar

An analogue of cyclosporin-A. Valspodar inhibits p-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activity of some drugs in some drug-resistant tumor cells. This agent also induces caspase-mediated apoptosis. (NCI04)

Valspodar is from the group

Multidrug Resistance Modulator

Other Names for Valspodar

Valspodar
6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]cyclosporin D
Amdray
Cyclo((2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl)-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-me
PSC 833
PSC-833
SZD PSC 833

Source

NCI Thesaurus License

Topics #4R #6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]cyclosporin D Amdray Cyclo((2S #6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl)-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-me PSC 833 PSC-833 SZD PSC 833 #Valspodar 6-[(2S