Definition of Triapine

A synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro. (NCI04)

Triapine is from the group

Ribonucleotide Reductase Inhibitor

Other Names for Triapine

Triapine
3-AP
3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone
3-Apct
3-aminopyridine-2-carboxaldehyde thiosemicarbazone

Source

NCI Thesaurus License

Topics #Triapine 3-AP 3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone 3-Apct 3-aminopyridine-2-carboxaldehyde thiosemicarbazone