Definition of Tolterodine Base

A benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects.

Tolterodine Base is from the group

Antimuscarinic Agent

Other Names for Tolterodine Base

Tolterodine
TOLTERODINE

Source

NCI Thesaurus License

Topics #Tolterodine TOLTERODINE