Epirubicin Base
Definition of Epirubicin Base A 4′-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. epirubicin intercalates into DNA and inhibits topoisomerase II,…
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Porfiromycin
Definition of Porfiromycin An N-methyl derivative of the antineoplastic antibiotic mitomycin c isolated from the bacterium streptomyces ardus and other…
Mitomycin A
Definition of Mitomycin A A methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium streptomyces caespitosus. Bioreduced mitomycin A generates oxygen radicals,…
Anastrozole
Definition of Anastrozole A nonsteroidal inhibitor of estrogen synthesis that resembles paclitaxel in chemical structure. As a third-generation aromatase inhibitor,…
Simvastatin
Definition of Simvastatin A lipid-lowering agent derived synthetically from a fermentation product of the fungus Aspergillus terreus. Hydrolyzed in vivo…
Dibenzo a i pyrene
Definition of Dibenzo a i pyrene An aromatic hydrocarbon that consists of six fused rings and is produced by the…
Dexmedetomidine
Definition of Dexmedetomidine An imidazole derivate and active d-isomer of medetomidine with analgesic, anxiolytic and sedative properties. Dexmedetomidine selectively binds…
Rizatriptan Benzoate
Definition of Rizatriptan Benzoate The benzoate salt form of rizatriptan, a member of the triptan class agents with anti-migraine property.…
Pravastatin Base
Definition of Pravastatin Base A synthetic lipid-lowering agent. pravastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme a (HMG-CoA) reductase, the enzyme which…