Definition of RTA 744

An anthracycline derivative with potential antitumor activity. RTA 744 intercalates into DNA and interrupts topoisomerase II activity, thereby inhibiting dna replication and repair, as well as RNA and protein synthesis. Unlike other anthracycline derivatives, RTA 744 crosses the blood-brain barrier and reaches therapeutic levels in the brain.

RTA 744 is from the group

Anthracycline Antibiotic

Other Names for RTA 744

Topoisomerase II Inhibitor RTA 744
RTA 744


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Topics #Topoisomerase II Inhibitor RTA 744 RTA 744 RTA-744