Definition of Oral Sodium Phenylbutyrate

An orally active derivative of the short-chain fatty acid butyrate with potential antineoplastic activity. 4-Phenylbutyrate inhibits histone deacetylase, resulting in gene expression modulation, reduced cell proliferation, increased cell differentiation, and apoptosis. This agent also initiates fragmentation of genomic DNA, resulting in decreased dna synthesis and the inhibition of tumor cell migration and invasion.

Oral Sodium Phenylbutyrate is from the group

Fatty Acid
Histone Deacetylase Inhibitor

Other Names for Oral Sodium Phenylbutyrate

Oral Sodium Phenylbutyrate

Source

NCI Thesaurus License

Topics #Oral Sodium Phenylbutyrate