Definition of NOVA Family

Expressed in brain (neurons or astrocytes), NOVA Family Genes encode NOVA Family nuclear proteins (NOVA1, NOVA2), autoantigens in POMA recognized by igg ANNA-2 that contain 3 KH domains and may regulate rna splicing in neurons and astrocytes. NOVA proteins form structural complexes with other proteins. Found as one or multiple copies of a conserved 70-aa motif in diverse nucleic acid binding, and other, proteins, the kh domain binds RNA — each motif appears necessary for binding. (NCI)

NOVA Family is from the group

Protein Family

Other Names for NOVA Family

NOVA Family

Source

NCI Thesaurus License

Topics #NOVA Family