Definition of Nortriptyline

The hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression. Nortriptyline blocks the norepinephrine presynaptic receptors, thereby blocking the reuptake of this neurotransmitter and raising the concentration in the synaptic cleft in the CNS. Nortriptyline also binds to alpha-adrenergic, histaminergic and cholinergic receptors. Long-term treatment with nortriptyline produces a downregulation of adrenergic receptors due to the increased stimulation of these receptors.

Nortriptyline is from the group

Antidepressant Agent

Other Names for Nortriptyline

Nortriptyline Hydrochloride
NORTRIPTYLINE HYDROCHLORIDE

Source

NCI Thesaurus License

Topics #Nortriptyline Hydrochloride NORTRIPTYLINE HYDROCHLORIDE