Definition of Methyldopa

A phenylalanine derivative and an aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure.

Methyldopa is from the group

Antihypertensive Agent
Dopamine Agonist

Other Names for Methyldopa

Methyldopa
3-Hydroxy-alpha-methyl-L-tyrosine
Aldomet
Amodopa
Dopamet
L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic Acid
Levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine
METHYLDOPA

Source

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Topics #4-Dihydroxyphenyl)-2-methylalanine METHYLDOPA #4-dihydroxyphenyl)propionic Acid Levo-3-(3 #Methyldopa 3-Hydroxy-alpha-methyl-L-tyrosine Aldomet Amodopa Dopamet L-2-Amino-2-methyl-3-(3