Definition of LMB-1 Immunotoxin

A chimeric protein consisting of the Fv portion of a monoclonal antibody attached to a fragment of Pseudomonas exotoxin A without its cell-binding region. LMB-1 immunotoxin targets B3, a Lewis Y-related carbohydrate epitope found on some solid tumors. The antibody attaches to the tumor cell and the exotoxin stops protein synthesis by inactivating elongation factor 2. (NCI04)

LMB-1 Immunotoxin is from the group

Immunotoxin

Other Names for LMB-1 Immunotoxin

LMB-1 Immunotoxin
B3-NLysPE38
Immunotoxin LMB-1
LMB-1
LMB-1 immunotoxin

Source

NCI Thesaurus License

Topics #LMB-1 Immunotoxin B3-NLysPE38 Immunotoxin LMB-1 LMB-1 LMB-1 immunotoxin