Definition of Imexon

A 2-cyanoaziridine derivative with antitumor activity in multiple myeloma. Although its mechanism of action is not clearly known, imexon may induce apoptosis via a pathway involving cleaved caspase-3, caspase-9, and/or caspase-8. Other cytotoxic mechanisms of action of this agent may involve thiol depletion, generation of reactive oxygen species (ROS), and decreases in the mitochondrial membrane potential. (NCI04)

Imexon is from the group

Biological Response Modifier

Other Names for Imexon

Imexon
4-imino-1,3-diazabicyclo[3,1,0]-hexan-2-one
Amplimexon
IMEXON

Source

NCI Thesaurus License

Topics #0]-hexan-2-one Amplimexon IMEXON #1 #3-diazabicyclo[3 #Imexon 4-imino-1