Definition of Gossypol

An orally-active polyphenolic aldehyde with potential antineoplastic activity. derived primarily from unrefined cottonseed oil, gossypol induces cell cycle arrest at the G0/G1 phase, thereby inhibiting dna replication and inducing apoptosis. This agent also inhibits cell-signaling enzymes, resulting in inhibition of cell growth, and may act as a male contraceptive.

Gossypol is from the group

Antineoplastic Plant Product
Protein Kinase C Inhibitor

Other Names for Gossypol

Gossypol
(2,2′-Binaphthalene)-8,8′-dicarboxaldehyde, 1,1′,6,6’7, 7′-hexahydroxy-5,5′-diisopropyl-3,3′-dimethyl-
1,1′,6,6′,7,7′-Hexahydroxy-3,3′-dimethyl-5,5′-bis(1-methylethyl)[2,2′-binaphthalene]-8,8′-dicarboxaldehyde
1,1′,6,6′,7,7′-Hexahydroxy-5,5′-diisopropyl-3-3′-dimethyl[2,2′-binaphthalene]-8,8′-dicarboxaldehyde
2,2′-bis[1,6,7-Trihydroxy-4-methyl-5-isopropyl-8-aldehydonaphthalene
2,2′-bis[8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene]
Cottonseed Meal Toxin
GOSSYPOL
Gossypol (Racemic)
gossypol

Source

NCI Thesaurus License

Topics #1 #2'-Binaphthalene)-8 #2'-bis[1 #2'-bis[8-Formyl-1 #3'-dimethyl- 1 #3'-dimethyl-5 #5'-bis(1-methylethyl)[2 #5'-diisopropyl-3 #5'-diisopropyl-3-3'-dimethyl[2 #6 #6'7 #7 #7-Trihydroxy-4-methyl-5-isopropyl-8-aldehydonaphthalene 2 #7-trihydroxy-5-isopropyl-3-methylnaphthalene] Cottonseed Meal Toxin GOSSYPOL Gossypol (Racemic) gossypol #7'-Hexahydroxy-3 #7'-hexahydroxy-5 #8'-dicarboxaldehyde #8'-dicarboxaldehyde 1 #8'-dicarboxaldehyde 2 #Gossypol (2