Definition of Exostosin-Like-2 Protein

Ubiquitously expressed by human EXTL2 Gene (EXT Family), 330-aa 37.5-kDa Exostosin-Like 2 is a type II membrane protein glycosyltransferase of the endoplasmic reticulum that initiates heparan sulfate/heparin biosynthesis by alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate and heparin chains. A soluble EXTL2 form, derived from proteolytic processing of the membrane form, is found in serum. (NCI)

Exostosin-Like-2 Protein is from the group

Glycosyltransferase

Other Names for Exostosin-Like-2 Protein

Exostosin-Like 2 Protein
Alpha-1,4-N-acetylhexosaminyltransferase EXTL2
Alpha-GalNAcT EXTL2
EXT-Related Protein 2
EXTL2

Source

NCI Thesaurus License

Topics #4-N-acetylhexosaminyltransferase EXTL2 Alpha-GalNAcT EXTL2 EXT-Related Protein 2 EXTL2 #Exostosin-Like 2 Protein Alpha-1