Definition of Carubicin

An anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting dna replication and ultimately, interfering with RNA and protein synthesis.

Carubicin is from the group

Anthracycline Antibiotic

Other Names for Carubicin

Carubicin
(2S,3S)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,10,12-tetrahydroxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(8S-cis)-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione
4-O-demethyldaunorubicin
5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3, 6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9, 10-tetrahydro-1,6,8,11-tetra-hydroxy- (8S-cis)- (8CI 9CI)
5,12-naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetra-hydroxy-(8S-cis)-(8CI 9CI)
5,12-naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetra-hydroxy-,(8S-cis)-(8CI)-(9CI)
CARMINOMYCIN
CMM
Carminomycin
Carminomycin I
Demethyldaunomycin
Karminomitsin
Karminomycin
NSC 180024

Source

NCI Thesaurus License

Topics #(8S-cis)-(8CI)-(9CI) CARMINOMYCIN CMM Carminomycin Carminomycin I Demethyldaunomycin Karminomitsin Karminomycin NSC 180024 #10 #10-tetrahydro-1 #11-dioxo-1-naphthacenyl 3-amino-2 #11-hexahydro-3 #11-tetra-hydroxy- #11-tetra-hydroxy- (8S-cis)- (8CI 9CI) 5 #11-tetrahydroxy-5 #12-Naphthacenedione #12-naphthacenedione 4-O-demethyldaunorubicin 5 #12-tetrahydroxy-6 #2 #3 #3S)-3-acetyl-1 #4 #5 #6 #6-trideoxy-alpha-L-lyxo-hexopyranoside (8S-cis)-acetyl-10-[(3-amino-2 #6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7 #8 #8-acetyl-10-[(3-amino-2 #9 #Carubicin (2S