Definition of Aryl Hydrocarbon Receptor Nuclear Translocator

Aryl hydrocarbon receptor Nuclear Translocator, encoded by the ARNT gene, heterodimers with HIF1A or EPAS1/HIF2A and functions as a transcriptional regulator of the adaptive response to hypoxia. Efficient dna binding requires dimerization with another bHLH protein. This nuclear protein is also required for activity of the Ah (dioxin) receptor and for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. (From Swiss-Prot and LocusLink)

Aryl Hydrocarbon Receptor Nuclear Translocator is from the group

Protein Complex Subunit

Other Names for Aryl Hydrocarbon Receptor Nuclear Translocator

Aryl Hydrocarbon Receptor Nuclear Translocator
ARNT
ARNT Protein
Dioxin Receptor, Nuclear Translocator
HIF-1 Beta
HIF-1Beta
HIF1-BETA
HIF1B
HIF1BETA
Hypoxia-Inducible Factor 1 Beta
Hypoxia-Inducible Factor 1, Beta Subunit

Source

NCI Thesaurus License

Topics #Aryl Hydrocarbon Receptor Nuclear Translocator ARNT ARNT Protein Dioxin Receptor #Beta Subunit #Nuclear Translocator HIF-1 Beta HIF-1Beta HIF1-BETA HIF1B HIF1BETA Hypoxia-Inducible Factor 1 Beta Hypoxia-Inducible Factor 1