Definition of Vitaxin

A humanized monoclonal IgG1 antibody directed against the vitronectin receptor alpha v beta 3 integrin. Humanized monoclonal antibody MEDI-522 blocks the binding of ligands, such as vitronectin, to alpha v beta 3 integrin, resulting in inhibition of angiogenesis and metastasis. Alpha v beta 3 integrin is a cell adhesion and signaling receptor that is expressed on the surface of tumor vessel endothelial cells, some tumor cells, and a number of other cell types.

Vitaxin is from the group

Endothelial-Specific Integrin-Survival Signaling Inhibitor
Monoclonal Antibody

Other Names for Vitaxin

Humanized Monoclonal Antibody MEDI-522
Abegrin
Humanized Monoclonal Antibody LM609
MEDI-522
Monoclonal Anti-Alpha V Beta 3 Integrin
Monoclonal Antibody Anti-Avb3 Integrin
Monoclonal Antibody Anti-alpha V Beta 3 Integrin MEDI-522
Monoclonal Antibody Anti-alpha V beta 3 Integrin
Vitaxin

Source

NCI Thesaurus License