Definition of Paclitaxel

A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell leukemia 2). (NCI04)

Paclitaxel is from the group

Taxane-Site Binding Agent
Taxane Compound

Other Names for Paclitaxel

Paclitaxel
5Beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one, 4,10-Diacetate 2-Benzoate 13-Ester with (2R,3S)-N-Benzoyl-3-phenylisoserine
Anzatax
Asotax
Bristaxol
PACLITAXEL
Praxel
Taxol
Taxol Konzentrat
[2aR-[2a Alpha,4beta,4a beta,6beta,9alpha(alphaR*,betaS*),-11alpha,12alpha,12a alpha,12b alpha]]-beta-(benzoylamino)-alpha-hydroxybenzene-propanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1a,33,4,-41,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-41,8,-12,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester
paclitaxel

Source

NCI Thesaurus License

Topics #-41 #10 #10-Diacetate 2-Benzoate 13-Ester with (2R #10beta #11 #11-dihydroxy-41 #11-methano-1H-cyclodeca(3 #11alpha #12 #12a #12a alpha #12alpha #12b alpha]]-beta-(benzoylamino)-alpha-hydroxybenzene-propanoic acid 6 #12b-bis(acetyloxy)-12-(benzoyloxy)-1a #12b-dodecahydro-4 #13-tetramethyl-5-oxo-7 #13alpha-hexahydroxytax-11-en-9-one #2-b]oxet-9-yl Ester paclitaxel #20-epoxy-1 #2alpha #3':3 #3S)-N-Benzoyl-3-phenylisoserine Anzatax Asotax Bristaxol PACLITAXEL Praxel Taxol Taxol Konzentrat [2aR-[2a Alpha #4 #4)benz(1 #4a beta #4beta #5 #6 #6beta #7beta #8 #9 #9alpha(alphaR* #betaS*) #Paclitaxel 5Beta