Definition of Nonsteroidal Antiinflammatory Drug

Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions — other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (MeSH)

Nonsteroidal Antiinflammatory Drug is from the group

Analgesic and Antipyretic

Other Names for Nonsteroidal Antiinflammatory Drug

Nonsteroidal Antiinflammatory Drug
NSAID
NSAIDs
nonsteroidal anti-inflammatory drugs

Source

NCI Thesaurus License

Topics #Nonsteroidal Antiinflammatory Drug NSAID NSAIDs nonsteroidal anti-inflammatory drugs