Definition of LGD 1550

An orally-active synthetic aromatic retinoic acid agent with potential antineoplastic and chemopreventive activities. LGD 1550 selectively binds to all three retinoic acid receptors (RAR-alpha, RAR-beta, and RAR-gamma), resulting in alterations in the expression of genes responsible for cell differentiation and proliferation. This agent also acts as an inhibitor of activator protein 1 (AP-1), a protein that mediates trophic responses and malignant transformation. (NCI04)

LGD 1550 is from the group

Retinoic Acid Agent

Other Names for LGD 1550

LGD 1550
(2E,4E,6E)-7-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-methyl-2,4,6-octatrienoic Acid


NCI Thesaurus License

Topics #1-dimethylethyl)phenyl]-3-methyl-2 #4 #4E #5-Bis(1 #6-octatrienoic Acid #6E)-7-[3 #LGD 1550 (2E