|A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14 — 18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
Follicular Lymphoma is from the group
Mature B-Cell Non-Hodgkin s Lymphoma
Other Names for Follicular Lymphoma
Follicle Center Lymphoma
Follicular Non-Hodgkin Lymphoma
Follicular Non-Hodgkin’s Lymphoma
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