Definition of DNA Damage

Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions that interfere with replication and transcription, as well as point mutations that disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair) — extensive damage can induce apoptosis.

DNA Damage is from the group

Pathologic Mutagenesis

Other Names for DNA Damage

DNA Damage

Source

NCI Thesaurus License

Topics #DNA Damage