Definition of Cinacalcet Hydrochloride

An oral calcimimetic. Cinacalcet hydrochloride increases the sensitivity of the calcium-sensing receptors on the chief cells in the parathyroid gland to extracellular calcium, thereby reducing parathyroid hormone secretion. A reduction in parathyroid hormone levels inhibits osteoclast activity, favourably impacts bone-specific alkaline phosphatase, bone turnover, and bone fibrosis, and leads to normalization of serum calcium and phosphate levels. Cinacalcet hydrochloride is a treatment option for primary and secondary hyperparathyroidism and parathyroid carcinoma.

Cinacalcet Hydrochloride is from the group

Malignancy-Associated Hypercalcemia Inhibitor

Other Names for Cinacalcet Hydrochloride

Cinacalcet Hydrochloride
1-Naphthalenemethanamine, a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-,(aR)-, Hydrochloride
CINACALCET HYDROCHLORIDE
Sensipar

Source

NCI Thesaurus License

Topics #(aR)- #a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)- #Cinacalcet Hydrochloride 1-Naphthalenemethanamine #Hydrochloride CINACALCET HYDROCHLORIDE Sensipar