Definition of 10-Deacetyltaxol

An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis.

10-Deacetyltaxol is from the group

Taxane-Site Binding Agent
Taxane Compound

Other Names for 10-Deacetyltaxol

10-Deacetyltaxol
benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))-

Source

NCI Thesaurus License

Topics #(2aR-(2aalpha #10 #10-Deacetyltaxol benzenepropanoic acid #11 #11-methano-1H-cyclodeca(3 #11-trihydroxy-4a #11alpha #12 #12a #12aalpha #12alpha #12b-(acetyloxy)-12-(benzoyloxy)-2a #12b-dodecahydro-4 #12balpha))- #13 #13-tetramethyl-5-oxo-7 #2-b)oxet-9-yl ester #3 #4 #4)benz(1 #4a #4abeta #4beta #5 #6 #6beta #8 #9 #9alpha(alphaR* #beta-(benzoylamino)-alpha-hydroxy- #betaS*)